New theory says autism and schizophrenia same disease

Their idea is, in broad outline, straightforward. Crespi and Badcock propose that an evolutionary tug of war between genes from the father’s sperm and the mother’s egg can, in effect, tip brain development in one of two ways. A strong bias toward the father pushes a developing brain along the autistic spectrum, toward a fascination with objects, patterns, mechanical systems, at the expense of social development. A bias toward the mother moves the growing brain along what the researchers call the psychotic spectrum, toward hypersensitivity to mood, their own and others’. This, according to the theory, increases a child’s risk of developing schizophrenia later on, as well as mood problems like bipolar disorder and depression.

In short: Autism and schizophrenia represent opposite ends of a spectrum that includes most, if not all, psychiatric and developmental brain disorders. The theory has no use for psychiatry’s many separate categories for disorders, and it would give genetic findings an entirely new dimension.

Full Story: the Chronicle Herald

2 Comments

  1. I always love to see things come together, grander schemes to fit together the smaller realities of life.. This seems like such a fitting idea..

  2. PKD seemed to identify the two, for instance in Martian Time-Slip.

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