Tagneuroscience

Mindful Cyborgs: Globalization, Writing and Japan

A quick catch-up episode in which Chris Dancy talks about his trip to Japan and the effects of globalization, and I talk a bit about the cognitive experience of writing. Here’s a taste:

One of them being this writer Arnon Grünberg who I think has actually might have been on Wired. I’m not sure. No. Where was it? Actually, it was New York Times. He is writing a book while he is connected to a bunch of sensors hundreds of sensors on his head, on his body and the book will be read by people wearing similar sensor. So, they have a bunch of volunteers to see if they can sync the feelings of what he wrote and what people experienced and I thought quite profound that we have almost a shared biological experience with the writing.

It was on November 29th. So, just couple of weeks ago in New York Times. Thoughts?

KF: That’s really interesting. I’d be curious to see what they find. I find the writing and reading are radically different experiences for me. So, I wouldn’t really expect the writer and the reader to really have synchronized experiences but I’m definitely curious to see how that plays out.

CD: I’ve never written fiction. So, if you’re like typing out a scene, I’m sure a lot of our listeners maybe aren’t writers, maybe some of them aren’t writers, professional, but when you’re doing science fiction and you’re in a really dramatic scene, you don’t get excited or you’re just seeing it and typing how it feels almost like you’re a court recorder or how does that work for you?

KF: Well, for me most of it . . . every writer’s different. I guess for me most of it is I already know what I’m going to write before I start typing it. So, by the time I’m trying to describe it, I think I’m a little bit more detached from the emotion of it and then the other thing to keep in mind is that. I don’t know what the saying is “75% of writing is rewriting” or whatever. Most of the time that you spend you spend on something is going to be revising it over and over again. So, I don’t know by the time you’re done, a lot of the visceral or emotional impact that you would expect to get from reading something is kind of worn off and you’re just sort of sick of reading the same sentence over and over again trying to figure out how to improve it.

CD: That’s really interesting.

KF: There are writers who don’t really know . . . I know that there are definitely a lot of writers who don’t really know what’s going to happen in a scene when they sit down and write it. I imagine that that would be kind of a different . . . they would be working in a very different state from me but I would still expect most of their time to be spent on rewriting and I would also expect . . . I would still expect like that feeling of sort of channeling creativity to be different from just reading it but again we’ll have to see how it plays out.

Download and Full Transcript Mindful Cyborgs: Episode 19 – Review, Musings, and Catch Up

Open Source, 3D Printable Brain Scanner, Brought to You by DARPA

Open BCI, an Open Source, 3D Printable Brain Scanner

My colleague Bob McMillan reports:

Conor Russomanno and Joel Murphy have a dream: They want to create an open-source brain scanner that you can print out at home, strap onto your head, and hook straight into your brainwaves.

This past week, they printed their first headset prototype on a 3-D printer, and WIRED has the first photos.

Bootstrapped with a little funding help from DARPA — the research arm of the Department of Defense — the device is known as OpenBCI . It includes sensors and a mini-computer that plugs into sensors on a black skull-grabbing piece of plastic called the “Spider Claw 3000,” which you print out on a 3-D printer. Put it all together, and it operates as a low-cost electroencephalography (EEG) brainwave scanner that connects to your PC.

Full Story: Wired: These Guys Are Creating a Brain Scanner You Can Print Out at Home

Computer Chips That Work Like a Brain Are Coming — Just Not Yet

I wrote for Wired about computer chips designed specifically for building neural networks:

Qualcomm is now preparing a line of computer chips that mimic the brain. Eventually, the chips could be used to power Siri or Google Now-style digital assistants, control robotic limbs, or pilot self-driving cars and autonomous drones, says Qualcomm director of product management Samir Kumar.

But don’t get too excited yet. The New York Times reported this week that Qualcomm plans to release a version of the chips in the coming year, and though that’s true, we won’t see any real hardware anytime soon. “We are going to be looking for a very small selection of partners to whom we’d make our hardware architecture available,” Kumar explains. “But it will just be an emulation of the architecture, not the chips themselves.”

Qualcomm calls the chips, which were first announced back in October, Zeroth, after the Isaac Asimov’s zeroth law of robotics: “A robot may not harm humanity, or, by inaction, allow humanity to come to harm.”

The Zeroth chips are based on a new architecture that radically departs from the architectures that have dominated computing for the past few decades. Instead, it mimics the structure of the human brain, which consists of billions of cells called neurons that work in tandem. Kumar explains that although the human brain does its processing much more slowly than digital computers, it’s able to complete certain types of calculations much more quickly and efficiently than a standard computer, because it can do many calculations at once.

Even the world’s largest supercomputers are able to use “only” one million processing cores at a time.

Full Story: Wired: Computer Chips That Work Like a Brain Are Coming — Just Not Yet

See also:

Palm Pilot Inventor Wants to Open Source the Human Brain

Yorkshire Pigs Control Computer Gear With Brain Waves

The End of Prozac Nation and the Rise of Deep Brain Stimulation

Vaughan Bell on the shift from psychiatric drugs that act on one specific neurotransmitter in favor of a “circuit” driven model of treating mental and neurological disorders:

In its place is a science focused on understanding the brain as a series of networks, each of which supports a different aspect of our experience and behaviour. By this analysis, the brain is a bit like a city: you can’t make sense of the bigger picture without knowing how everything interacts. Relatively few residents of Belfast who live in the Shankill spend their money in the Falls Road and this tells us much more about the city – as these are the key loyalist and republican areas – than knowing that the average income of each area is much the same. Similarly, knowing that key brain areas interact differently when someone gets depressed tells us something important that a measure of average brain activity would miss. […]

Perhaps more surprising for some is the explosion in deep brain stimulation procedures, where electrodes are implanted in the brains of patients to alter electronically the activity in specific neural circuits. Medtronic, just one of the manufacturers of these devices, claims that its stimulators have been used in more than 100,000 patients. Most of these involve well-tested and validated treatments for Parkinson’s disease, but increasingly they are being trialled for a wider range of problems. Recent studies have examined direct brain stimulation for treating pain, epilepsy, eating disorders, addiction, controlling aggression, enhancing memory and for intervening in a range of other behavioural problems.

Full Story: The Guardian: Changing brains: why neuroscience is ending the Prozac era

See Also:

Deep brain stimulation to treat depression

The Curious Case of a Woman Addicted to Her Brain Implant

Not Science Fiction: A Brain In A Box To Let People Live On After Death

Fast Company on the latest in neurotech:

While their roundtable discussion admittedly sounded like a master’s exercise in strange science, the kicker is that all three are engaged in preliminary efforts to make this happen. Last year, at the resolutely mainstream MIT Media Lab, I saw Dr. Berger speak about hacking the memories of rats. Berger’s lab at USC is actively working on prosthetic brain implants that both falsify memories and stimulate brain function in damaged neurons. The lab’s work recently received media attention when it successfully generated new memories in a rat that had its hippocampus chemically disabled. In literature, Berger emphasizes his technology’s potential for treating Alzheimer’s and dementia through the possibility of “building spare parts for the brain;” on-stage in New York, he said it could also lead in the future to full-on brain transplants.

This would work in tandem with Kaplan’s and Lebedev’s specialties. The two Russian scientists research brain-computer interfaces (BCIs)–plug-in interfaces which meld the human brain and nervous system to computer operating systems. While BCIs are most commonly found in toys that read brainwaves to detect stress or concentration, they have revolutionary potential to change the lives of stroke victims and the disabled.

Full Story: Fast CoExist: Not Science Fiction: A Brain In A Box To Let People Live On After Death

Doctors Worry About DIY Brain Shocks

Dave Siever of Mind Alive

A recent paper published in the Journal of Medical Ethics warns of the dangers of DIY transcranial direct current stimulation (tDCS). The National Post reports:

Those risks include reversing the polarity of the electrodes to cause impairment instead of benefit, and triggering potentially long-lasting and negative changes to the brain’s biology, the researchers argue in the Journal of Medical Ethics. […]

In fact, Health Canada considers tDCS machines to be class-three devices — on a scale of risk ranging from one to four — and has yet to approve any for treating psychological illness – though they are licensed for pain and insomnia therapy, said Leslie Meerburg, a department spokeswoman. […]

One subtle but troubling risk could lie in the ability of the devices to change behaviour, with research by Prof. Fecteau and colleagues suggesting tDCS can actually make people better liars, or less empathetic, both qualities that could encourage unscrupulous conduct.

Full Story: Do-it-yourself brain stimulation has scientists worried as healthy people try to make their minds work better

Amusingly, after citing a researcher who says tDCS could make people better liars and less empathetic, the Post quotes someone selling a home tDCS rig saying that it is “very safe.” But, despite the somewhat sordid tone of the story, the actual paper Medical Ethics paper does say that tDCS is “relatively safe.” You can find the full paper here.

(via Theoretick)

What’s Wrong With Cognitive Neuroscience

Neuroskeptic writes:

Talking about something in a neurobiological way sends the message that this is a neurobiological issue. In this way, many fMRI papers serve to spread the idea that this is an issue that only neuroscience can solve and, therefore, create a demand for more fMRI studies. The authors of this paper are victims of this mentality, a widespread confusion about what neuroscience is for.

fMRI is a great way to approach neuroscientific questions. It’s a bad (and terribly expensive) way to do psychology. This study is about psychology, and should not have involved an MRI scanner.

Full Story: Neuroskeptic: Looking Askance At Cognitive Neuroscience

See also: Think brain scans can reveal our innermost thoughts? Think again

The Quantified Brain of a Self-Tracking Neuroscientist

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The MIT Technology Review reports:

Russell Poldrack, a neuroscientist at the University of Texas at Austin, is undertaking some intense introspection. Every day, he tracks his mood and mental state, what he ate, and how much time he spent outdoors. Twice a week, he gets his brain scanned in an MRI machine. And once a week, he has his blood drawn so that it can be analyzed for hormones and gene activity levels. Poldrack plans to gather a year’s worth of brain and body data to answer an unexplored question in the neuroscience community: how do brain networks behave and change over a year?

Full Story: MIT Technology Review: The Quantified Brain of a Self-Tracking Neuroscientist

DMT Found in the Pineal Gland of Live Rats

DMT: The Spirit Molecule author Rick Strassman’s organization the Cottonwood Research Foundation announces:

We’re excited to announce the acceptance for publication of a paper documenting the presence of DMT in the pineal glands of live rodents. The paper will appear in the journal Biomedical Chromatography and describes experiments that took place in Dr. Jimo Borjigin’s laboratory at the University of Michigan, where samples were collected. These samples were analyzed in Dr. Steven Barker’s laboratory at Louisiana State University, using methods that funding from the Cottonwood Research Foundation helped develop.

The pineal gland has been an object of great interest regarding consciousness for thousands of years, and a pineal source of DMT would help support a role for this enigmatic gland in unusual states of consciousness. Research at the University of Wisconsin has recently demonstrated the presence of the DMT-synthesizing enzyme as well as activity of the gene responsible for the enzyme in pineal (and retina). Our new data now establish that the enzyme actively produces DMT in the pineal.

The next step is to determine the presence of DMT in cerebrospinal fluid (CSF), the fluid that bathes the brain and pineal. CSF is a possible route for pineal-synthesized DMT to effect changes in brain function. Successfully establishing DMT’s presence in this gland adds another link in the chain between the pineal and consciousness and opens new avenues for research.

Full Story: Cottonwood Research Foundation: DMT Found in the Pineal Gland of Live Rats

(via Disinfo)

Previously: Scientific Evidence of Psychedelic Body Fluids

Understanding The Brain Of A Man With No Conscious Memory

Fascinating:

The primary problem E.P. experienced came in what we’d probably call conscious memory, or what professionals call declarative memory. This involves, as the names imply, the ability to be aware of something we know, and to state it, whether it’s a historic event or the term for an obscure object. For example, E.P. moved to San Diego shortly after his illness, but he was never able to consciously remember the layout of his apartment or where the Pacific Ocean was, even though it was two miles from home. And although he could relate stories about the events of his youth, he’d often get repetitive while doing so—after all, he couldn’t remember which parts of the stories he’d already related.

But that doesn’t mean he had no memory. We store short-term information (like the digits we’re carrying when we’re doing math) in a place called working memory—and E.P.’s working memory was just fine. In some tests, he was blindfolded and led along a path up to 15 meters in length. When it was over, he was able to remember his start position successfully. But wait a few minutes, and the entire test faded from his memory. When asked, he’d tell the researchers that he’d been “in conversation” a few minutes earlier.

Full Story: Ars Technica: Understanding the brain of a man with no conscious memory

(Remind anyone of Memento?)

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