Update: Please see this update on how, although this research is significant, it doesn’t necessarily indicate that there is arsenic-based bacteria in the wild.

Evidence that the toxic element arsenic can replace the essential nutrient phosphorus in biomolecules of a naturally occurring bacterium expands the scope of the search for life beyond Earth, according to Arizona State University scientists who are part of a NASA-funded research team reporting findings in the Dec. 2 online Science Express.

It is well established that all known life requires phosphorus, usually in the form of inorganic phosphate. In recent years, however, astrobiologists, including Arizona State University professors Ariel Anbar and Paul Davies, have stepped up conversations about alternative forms of life. […]

Davies has previously speculated that forms of life different from our own, dubbed “weird life,” might even exist side-by-side with known life on Earth, in a sort of “shadow biosphere.” The particular idea that arsenic, which lies directly below phosphorous on the periodic table, might substitute for phosphorus in life on Earth, was proposed by Wolfe-Simon and developed into a collaboration with Davies and Anbar. Their hypothesis was published in January 2009, in a paper titled “Did nature also choose arsenic?” in the International Journal of Astrobiology.

PhysOrg: Deadly arsenic breathes life into organisms